Product Description
Fypryst Combo Spot-On Solution for Dogs (20-40 kg)
Product Overview
Fypryst Combo is a broad-spectrum antiparasitic spot-on solution for large dogs weighing between 20 kg and 40 kg . Manufactured by KRKA, d.d., Slovenia, this veterinary medicine combines two active ingredients: fipronil, which kills adult fleas and ticks, and (S)-methoprene, an insect growth regulator (IGR) that prevents flea eggs, larvae, and pupae from developing into adults .
Key Specifications
Key Benefits
Indications for Use
Fypryst Combo is indicated for the treatment and prevention of:
| Parasite Type | Specific Parasites | Efficacy Duration |
|---|---|---|
| Fleas | Ctenocephalides spp. | Up to 8 weeks |
| Ticks | Ixodes ricinus, Dermacentor variabilis, Dermacentor reticulatus, Rhipicephalus sanguineus | Up to 4 weeks |
| Biting Lice | Trichodectes canis | Effective |
Dosage and Administration
Dosage: One 2.68 ml pipette per dog weighing between 20 kg and 40 kg .
Application Instructions:
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Hold the pipette upright, twist the pipette cap, and pull it off .
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Turn the cap around and place the other end back on the pipette. Push and twist the cap to break the seal, then remove the cap .
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Part the dog's coat at the base of the neck in front of the shoulder blades until the skin is visible .
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Place the tip of the pipette onto the skin and squeeze the pipette several times to empty the entire contents directly onto the skin in one spot .
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Temporary changes to the coat (clumped/greasy hair) may be observed at the application site .
Safety Information
Contraindications:
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Do not use in puppies less than 8 weeks of age and/or weighing less than 2 kg .
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Do not use on sick animals (systemic diseases, fever) or convalescent animals .
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Do not use in rabbits — adverse reactions or even death may occur .
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This product is specifically developed for dogs. Do not use in cats and ferrets, as this could lead to overdosing .
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Do not use in case of hypersensitivity to the active substances or any excipients .
Precautions for Animals:
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Apply to an area where the animal cannot lick it off, and ensure animals do not lick each other following treatment .
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Bathing/immersion in water within 2 days after application should be avoided .
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Weekly bathing may reduce the duration of protection against fleas to approximately 5 weeks .
User Precautions:
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This product can cause mucous membrane, skin, and eye irritation .
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People with a known hypersensitivity to insecticides or alcohol should avoid contact with the product .
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Treated animals should not be handled until the application site is dry. Children should not be allowed to play with treated animals until the application site is dry .
Environmental Precautions:
Adverse Reactions
Among the very rare suspected adverse reactions:


